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Yang等發(fā)現(xiàn)，與新學(xué)技能有關(guān)的神經(jīng)活動(dòng)會(huì)在睡眠時(shí)被重新激活。研究人員說，這一重新激活與突觸棘生長(zhǎng)相關(guān)聯(lián)，這就是睡眠是如何促成記憶增進(jìn)及改善行為執(zhí)行的。他們的結(jié)果提示，睡眠可導(dǎo)致新突觸的生長(zhǎng)。以往的研究顯示，在睡眠時(shí)突觸數(shù)的減少通常與特殊的訓(xùn)練——如在本研究中的訓(xùn)練——無關(guān)。
Yang等人提出，也許在zui近的經(jīng)驗(yàn)中形成的突觸會(huì)在睡眠時(shí)得到強(qiáng)化，而代表較為遙遠(yuǎn)記憶的突觸則會(huì)在睡眠中被下調(diào)，以在腦中給其它的、資訊更為相關(guān)的突觸騰出位置。一則《觀點(diǎn)欄目》文章提出了更多的見解。
吃，跟呼吸和睡眠一樣，似乎是一個(gè)相當(dāng)基本的生物任務(wù)。然而，咀嚼需要舌頭和下顎之間復(fù)雜的相互作用，舌頭將食物定位于牙齒之間，然后每次移動(dòng)下頜夾磨起來。如果這個(gè)動(dòng)作沒有精確的協(xié)調(diào)，咀嚼口香糖的人會(huì)不幸地咬到舌頭。
杜克大學(xué)的研究人員利用*跟蹤技術(shù)，尋找小鼠進(jìn)餐時(shí)間保持相對(duì)無痛的潛在的大腦回路。這項(xiàng)研究發(fā)表于6月3日的eLife網(wǎng)絡(luò)版上，可以有助于洞察從夜間磨牙到微笑或復(fù)雜的發(fā)聲的人類各種行為。
在小鼠大腦的這個(gè)藍(lán)色的橫截面，兩種顏色的熒光染料追蹤調(diào)節(jié)下頜關(guān)閉和觸動(dòng)舌頭伸出的前運(yùn)動(dòng)神經(jīng)元，揭示大腦在咀嚼，飲水和發(fā)聲過程中是如何連接協(xié)調(diào)這些肌肉的。圖片來源：王帆實(shí)驗(yàn)室/杜克大學(xué)
“咀嚼是你可以有意識(shí)地控制的一種行為，但如果你停止關(guān)注大腦中的這些相互連接的神經(jīng)元，實(shí)際上，這一切都是它們?yōu)榱四阕龅模?rdquo;這項(xiàng)研究的主要作者、杜克大學(xué)醫(yī)學(xué)院研究生愛德華斯坦尼克四世說。“我們有興趣了解這一切是如何工作的，而*步是搞清楚這些神經(jīng)元所在。”

Yang et al found that neural activity associated with new learning skills was reactivated during sleep. The researchers said that this reactivation is associated with spine spine growth, which is how sleep contributes to memory enhancement and improved performance. Their results suggest that sleep can lead to the growth of new synapses. Previous studies have shown that the reduction in the number of synapses during sleep is usually not associated with special training, such as training in this study.
Yang et al. Suggest that synapses, perhaps formed in recent experience, may be enhanced during sleep and that synapses, representing more distant memories, may be downgraded during sleep to give other, more relevant, information in the brain The synapses make place. A "point of view" article put forward more insights.
Eating, like breathing and sleeping, seems like a fairly basic biological task. However, chewing requires complex interactions between the tongue and the jaw, the tongue locates the food between the teeth, and then moves the mandrel around each time it rubs up. If this action is not coordinated precisely, those who chew chewing gum will bite the tongue unluckily.
Researchers at Duke University use advanced tracking technology to look for potential brain circuits in mice that stay relatively painless for mealtime. The study, published on eLife's online version on June 3, can help to visualize various human behaviors from night molars to smiles or complex vocalizations.
In this blue cross-section of the mouse brain, two color fluorescent dyes track the front motor neurons that regulate jaw closing and touch the tongue's extension, revealing how the brain coordinates and coordinates these muscles during chewing, drinking and vocalizations . Image Source: Wang Fan Laboratory / Duke University
"Chewing is an act you can consciously control, but if you stop focusing on these interconnected neurons in the brain, in fact it's all they did for you," said lead author of the study, Du Edward College Medical College graduate Edward IV said. "We are interested in learning how this all works and the first step is to figure out where these neurons are."